WebDec 6, 2024 · Exposure of the citrus seeds to tryptoquialanine A resulted in a complete inhibition of germination and an altered metabolic response. Since this phytotoxic effect requires the extracellular export of tryptoquialanine A, we investigated the mechanisms of extracellular delivery of this alkaloid in P. digitatum . WebDec 3, 2024 · 34 tryptoquialanine A resulted in a complete inhibition of germination and an altered 35 metabolic response. Since this phytotoxic effect requires the extracellular …
Structure, composition and biological properties of fungal ...
WebMar 9, 2016 · Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicum. J. Am. Chem. Soc. 133, 2729–2741 (2011). WebSep 13, 2024 · Tryptoquialanine and meleagrin biosynthesis from L-tryptophan in P. aethiopicum and P. chrysogenum by respective biosynthetic genes (Gao et al. 2011; García-Estrada et al. 2011). Communesin F biosynthesis from L-tryptophan, tryptamine, and 4-dimethylallyl-L-tryptophan in P. expansum with respective biosynthetic genes (Lin et al. … ios hittest
Fungal Indole Alkaloid Biosynthesis: Genetic and Biochemical ...
WebFeb 17, 2024 · Tryptoquialanine A, Tryptoquialanine C, 15-dimethyl-2-epi-fumiquinazoline A, deoxytryptoquialanone, Citrinadin A, Deoxycitrinadin A, Chrysogenamide A [33,34] J. Fungi 2024, 7, 147 4 of 16 Table 1. Cont. Medicinal Plant Endophytic Fungi Bioactive Compounds/Effects References WebTryptoquialanine (Figure 6) is a quinazoline-containing indole alkaloid produced by P. aethiopicum. It is structurally similar to a known tremorgenic mycotoxin from A. clavatus tryptoquivaline. Due to the presence of the non-proteinogenic aa anthranilic acid in the scaffold of the peptide, it was inferred that the compound is assembled by a NRPS ( Ames … WebFeb 1, 2024 · The calpinactam synthetase CalA (712 kDa) is approximately one and a half the size of the largest heterologously NRPSs produced in S. cerevisiae, among them the α-l-aminoadipyl-l-cysteinyl-d-valine synthetase PcbAB (426 kDa), the fumiquinazoline F synthetase Afu6g12080 (438 kDa), the tryptoquialanine synthetase TqaA (450 kDa) and … on this blessed day