Topcat trial heart failure
WebCardiac structure and function and prognosis in heart failure with preserved ejection fraction: findings from the echocardiographic study of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial. Circ Heart Fail. 2014; 7:740–751. doi: 10.1161/CIRCHEARTFAILURE.114.001583 Link Google Scholar; 100. WebMethods and results: Using data from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, a frailty index (FI) was …
Topcat trial heart failure
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Web6.1.5 Myocardial injury, myocyte death, and troponins. In the Valsartan in Heart Failure Trial (Val-HeFT), 10.4% of subjects had detectable cardiac troponin T (cTnT) with a fourth-generation clinical assay (detection limit 0.01 ng/mL) and this proportion increased to 92% when an hs assay (hs-cTnT; detection limit 0.001 ng/mL) was used. Although the … Web13. apr 2024 · This study aims to describe baseline characteristics and in-hospital management of a patient cohort hospitalized with acute heart failure (AHF). Adult patients in Denmark admitted with a medical diagnosis during a 7-day period were reviewed for symptoms and clinical findings suggestive of AHF. HFpEF was defined as LVEF ≥ 45%. Of …
Web15. okt 2004 · Cardiac structure and function and prognosis in heart failure with preserved ejection fraction: findings from the echocardiographic study of the Treatment of … WebPred 1 dňom · The DOHAS (Dialysis Outcomes Heart Failure Aldactone Study) trial, a prospective, multicenter, randomized controlled, open-label trial in 5 Japanese centers, …
Web25. feb 2024 · Methods: The study cohort was comprised of participants from the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist …
Web18. nov 2024 · Introduction. Heart failure with preserved ejection fraction (HFpEF) is a common and increasingly prevalent clinical syndrome, broadly characterized by signs and symptoms of heart failure (HF), in the absence of a reduced left ventricular ejection fraction (LVEF). 1 The HFpEF definition is based on the assumption that LVEF >45% is not only the …
Webthe TOPCAT trial (n5205). Associations were validated in a participant-level meta-analysis (n5810) that included participants with HFpEF from the PHFS study (United ... heart … icc fopWeb20. feb 2024 · The TOPCAT trial evaluated the effectiveness of aldosterone antagonist therapy in reducing cardiovascular mortality, aborted cardiac arrest, and heart failure … icc for binary dataWeb8. aug 2024 · The TOPCAT trial showed no benefit for spironolactone in heart failure patients with preserved ejection fraction (HFpEF). Post-hoc, spironolactone helped participants from the Americas, but not Eastern Europe. Determining which patients with HFpEF could respond like TOPCAT's responders should help guide their care. icc for binary outcomeWeb22. aug 2024 · Design, Setting, and Participants. This secondary analysis of the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial (TOPCAT) evaluated the distribution and prognostic significance of NPs across 6 subgroups comprising 1057 adult patients (60%) in the Americas region of TOPCAT with … icc football stadiumWeb6. jan 2015 · Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) patients with heart failure and preserved left ventricular ejection … icc for 7500 or 7500sl cryostatsWebAlthough patients with heart failure and preserved ejection fraction (HF-PEF) represent nearly half of the population with chronic heart failure, few evidence-b ... (TOPCAT) trial … moneyfarm robo advisorWebAlthough patients with heart failure and preserved ejection fraction (HF-PEF) represent nearly half of the population with chronic heart failure, few evidence-based medical therapies are available. The neutral overall results of the TOPCAT trial of spironolactone in HF-PEF leave clinicians who treat heart failure with an ongoing clinical dilemma. money farm reaper 2