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WebAbstract: Esophagogastric junction outflow obstruction (EGJOO) is an abnormal topographic pattern seen on high-resolution mano-metry. EGJOO is characterized by an elevated median integrated relaxation pressure with intact or weak peristalsis, thus not meeting the criteria for achalasia. WebOct 2, 2013 · Introduction. The lipid messenger PGE 2 is a major downstream product of arachidonic acid metabolism by the cyclooxygenases COX-1 and COX-2, and mediates innate and adaptive immune responses in allergic inflammation, autoimmune diseases, asthma, nociception, and chronic neurodegenerative disorders. While PGE 2 is a well … 3兩3錢
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