Hipec cisplatin sodium thiosulfate
WebbThe use of intraperitoneal cisplatin (CDDP) is associated with a risk of acute kidney … Webb30 dec. 2024 · Patients undergo cytoreduction. Patients also undergo HIPEC over 60 …
Hipec cisplatin sodium thiosulfate
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Webb1 jan. 2024 · Cisplatin, up to 250 mg/m2 over 90 min, appeared as the key HIPEC drug with a toxicity profile well controlled by the concomitant intravenous perfusion of sodium thiosulfate. WebbImproved survival from childhood cancer has been achieved at the cost of long-term comorbidities that reduce quality of life. The chemotherapy agent cisplatin is essential for treatment of many paediatric and adolescent malignancies but in a large proportion of patients results in cisplatin-induced hearing loss, a debilitating and permanent late …
Webb3 dec. 2024 · HIPEC was performed at the end of the cytoreductive procedure via the open technique with cisplatin (100 mg/m 2). The HIPEC procedure lasted approximately 120 minutes, ... To prevent nephrotoxicity, sodium thiosulfate was administered at the start of perfusion and as a continuous infusion over 6 hours postoperatively. Interpretation ... Webbtherapy (HIPEC) with cisplatin has been shown to improve overall sur- vival in …
Webb14 juli 2024 · Remarkably, clinical evidence for strategies to prevent cisplatin-induced AKI is scarce. Van Driel et al., who did not observe significant nephrotoxicity in a collective of 118 patients treated with cisplatin HIPEC, routinely applied administered sodium thiosulphate (9 g/m 2) to prevent nephrotoxicity. Webb1 jan. 2024 · Cisplatin, up to 250 mg/m2 over 90 min, appeared as the key HIPEC drug …
Webbnephrotoxicity following HIPEC with delayed treatment with sodium thiosulfate (STS). This case suggests a new utility for this agent in rescue of severe cisplatin nephrotoxicity remote from ...
Webb21 juni 2024 · Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss. … ifix knowledge baseWebb2 maj 2024 · Objectives: Cisplatin is commonly used during intraperitoneal … issresearch.comWebbHIPEC was administered at the end of the cytoreductive surgical procedure with the use … ifix kernowWebb4 mars 2024 · Goel R., Cleary S.M., Horton C. Effect of sodium thiosulfate on the pharmacokinetics and toxicity of cisplatin. J. Natl Cancer Inst. 1989; 81 (20):1552–1560. [Google Scholar] Laplace N., Kepenekian V., Friggeri A. Sodium Thiosulfate Protects from Renal Impairement Following Hyperthermic Intraperitoneal Chemotherapy … ifixit z fold 3Webb2 juni 2024 · Sodium thiosulfate (ST) has been suggested as a nephroprotectant for patients undergoing HIPEC with cisplatin. Methods: A feasibility trial (ClinicalTrials.gov: NCT01970722) evaluated safety outcomes of HIPEC with cisplatin 75 mg/m 2 during optimal cytoreductive surgery (CRS) in patients with EOC and endometrial cancer (n = … ifixitzone walnut californiaiss research super vitamin pakWebb1 aug. 2024 · A combined approach, incorporating careful intra operative fluid … ifixit官网打不开