Cullin family protein binding

Author: bknc

August undefined, 2024

WebDec 4, 2024 · Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2024] DCUN1D4 defective in cullin neddylation 1 domain containing 4 [ (human)] WebApr 27, 2024 · The Cullin-RING ligases (CRL), encompassing Cullin family proteins as scaffold components, are the largest class of RING-type E3 ubiquitin ligases that mediate polyubiquitination of...

De novo variants in CUL3 are associated with global

WebIts expression is induced by heat shock. HSP47 is expressed in the endoplasmic reticulum. These cells synthesize and secrete type I and type II collagen. [7] The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. WebCullin-4A is a protein that in humans is encoded by the CUL4A gene. CUL4A belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle.As a result, … phish indianapolis 2022

37713 - Gene ResultSkpF SKP1-related F [ (fruit fly)]

WebCullin RING ubiquitin E3 ligases (CRL) is the largest family of ubiquitin E3 ligases. In fact, CRL is a multiprotein complex, in which cullin serves as a scaffold linking a ubiquitin … WebMay 2, 2016 · We identified that several putative miRNA target genes like Cullin 2 (CUL2), member RAS oncogene family (RAB6A), UBE2I, clathrin heavy chain 1 (CLTC), Desmocollin 3 (DSC3), Ras Family Small GTP Binding Protein (RAP1B), LSM12 homolog (LSM12), protocadherin 11 X-linked (PCDH11X) and HCLS1 Associated Protein X-1 … WebNov 28, 2024 · Recently, a novel ubiquitin-binding domain was identified at the C-terminal end of KHNYN (also called KIAA0323) protein. This domain, called CUBAN for cullin binding domain associating with NEDD8, shows a clear preference for monomeric NEDD8 and mediates the interaction of KHNYN with neddylated cullins [10,11]. Although the … phishing 101 crossword answers

CUL4A - Wikipedia

WebApr 28, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin protein family comprises eight members (CUL1 to CUL7 and PARC), which are … WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex-dependent ubiquitination and subsequent degradation of downstream substrates. Naive T cells could be activated and differentiated into effector and memory T cells by exogenous … tsp stationeryWebMar 21, 2024 · Summary Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024] phishine

"WebOct 31, 2024 · Cullin (CUL) proteins have critical roles in development and cancer, however few studies on CUL7 have been reported due to its characteristic molecular … " - Cullin family protein binding

Cullin family protein binding

anti-DREAM Antibody from antibodies-online - biocompare.com

WebMar 21, 2024 · Enables cullin family protein binding activity. Involved in cellular response to DNA damage stimulus; positive regulation of protein neddylation; and regulation of cell growth. Located in nucleus and spindle. [provided by Alliance of Genome Resources, Apr 2024] GeneCards Summary for DCUN1D5 Gene http://amigo.geneontology.org/amigo/term/GO:0005515

Did you know?

WebDec 8, 2024 · Summary Predicted to enable cullin family protein binding activity and ubiquitin-ubiquitin ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of mitotic metaphase/anaphase transition; protein K11-linked ubiquitination; and ubiquitin-dependent protein catabolic … Web1 day ago · Targeting oncofusion proteins is an attractive approach for cancer treatment. First, fusion proteins are specifically expressed in cancer cells rather than in normal cells. Accordingly, the specific targeting of fusion proteins potentially offers limited toxicity. Furthermore, fusion proteins may be the sole driver of some cancers, making them ...

WebNov 25, 2024 · The largest family of this type is the Cullin-RING E3 ligase (CRL) complex family, with over 200 members [17,18]. Within this family, the CRL1 or S phase kinase-associated protein 1 (S kp1)-C ullin 1-F-box protein (SCF) E3 ligases are the best characterized . In these ligases, the CRL scaffold, Cullin 1 (Cul1), binds the Skp1 … WebDec 4, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin …

WebApr 12, 2024 · This variant Spry2 behavior, linked to specific stimuli or cell types, seems to depend on its binding to protein phosphatase 2 A (PP2A) and the resulting dephosphorylation of certain residues of ... WebProduct Characteristics: The DCN1-like protein family is comprised of Dcun1D1, Dcun1D2, Dcun1D3, Dcun1D4 and Dcun1D5. The founding member, Dcun1D1, is involved in the …

WebMar 21, 2024 · Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024]

WebNov 24, 2024 · Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SKP1 (S-phase kinase associated protein 1). [provided … phish infant onesieWebNov 6, 2024 · Gene ID: 84259, updated on 6-Nov-2024 Summary Enables cullin family protein binding activity. Involved in cellular response to DNA damage stimulus; positive regulation of protein neddylation; and regulation of cell growth. Located in nucleus and spindle. [provided by Alliance of Genome Resources, Apr 2024] Other designations tsp state taxWebWerner helicase interacting protein 1 (WRNIP1) is a ubiquitin-binding protein that undergoes extensive post-translational modification including ubiquitination, sumoylation, … phish indyWebOct 13, 2024 · Gene ID: 54638, updated on 13-Oct-2024 Summary Predicted to enable cullin family protein binding activity. Predicted to be involved in several processes, including cytoplasmic sequestering of NF-kappaB; regulation of I-kappaB kinase/NF-kappaB signaling; and vesicle-mediated transport to the plasma membrane. tsp status code yWebThe evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of … phish infant burpeeWebThe evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of three founding cullins conserved from yeast to humans, uses a large beta-propeller protein, DDB1, as a linker to interact with … CRL4s: the CUL4-RING E3 ubiquitin ligases phish in eugene oregonWebMembers of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that … phishing 101